Christine Brown is an ambitious L.A. loan officer with a charming boyfriend, professor Clay Dalton. Life is good until the mysterious Mrs. Ganush arrives at the bank to beg for an extension on her home loan. Should Christine follow her instincts and give the old woman a break? Or should she deny the extension to impress her boss, Mr. Jacks, and get a leg-up on a promotion? Christine fatefully chooses the latter, shaming Mrs. Ganush and dispossessing her of her home. In retaliation, the old woman places the powerful curse of the Lamia on Christine, transforming her life into a living hell.